
Quality is measured, not assumed. Every lot is supplied with a batch-specific Certificate of Analysis that documents what was tested, the method used, and the result. Here is exactly what that process checks.
The process
Each lot moves through the same sequence before it reaches a researcher's bench. A lot that does not meet the listed specifications is not released.
01
The compound is confirmed by LC-MS (mass spectrometry) against its expected structure.
02
Assay purity is measured by RP-HPLC against a specification of ≥ 98.0%.
03
Net peptide or fill content, water, acetate and related substances are quantified.
04
Bacterial endotoxins are tested by LAL assay; the lot is documented and released.
What is measured
These are the parameters that appear on an FNA Certificate of Analysis, with the method used for each.
| Test item | Method | What it confirms |
|---|---|---|
| Identity | LC-MS / ESI-MS | The compound matches its expected molecular identity. |
| Assay purity | RP-HPLC (UV) | Percentage of target compound vs related substances (spec ≥ 98.0%). |
| Net peptide / fill content | Gravimetric / UV (dry basis) | Actual peptide mass in the vial, beyond the label figure. |
| Water content | Karl Fischer titration | Residual moisture in the lyophilized powder. |
| Acetate / counter-ion | Ion chromatography | Counter-ion fraction of the total mass. |
| Related substances | RP-HPLC | Total impurities (spec ≤ 2.0%). |
| Bacterial endotoxins | LAL assay | Endotoxin level (spec < 2 EU/mg; < 0.5 for NAD+). |
| Copper content (GHK-Cu) | ICP-MS | Copper conforms to the complex structure. |
| pH & residual solvents (NAD+) | pH / ICH Q3C | Solution pH in range; residual solvents within limits. |
How to verify
Each lot moves through the same sequence before it reaches a researcher's bench. A lot that does not meet the listed specifications is not released.
01
The lot number is printed on the vial and matches its Certificate of Analysis. They should be identical.
02
Check the assay purity, net peptide content and endotoxin result against the specification column on the report.
03
You can request the certificate for any lot before you order, on the COA request page.
Documentation, not adjectives
Browse every Certificate of Analysis on file, or request the report for a specific lot.
FDA & Legal Disclaimer. The statements on this website have not been evaluated by the U.S. Food and Drug Administration. Products offered by FNA Peptides are not intended to diagnose, treat, cure, or prevent any disease. All products are sold for laboratory and research use only and are not for human or veterinary consumption. FNA Peptides is a chemical supplier and is not a compounding pharmacy under Section 503A, nor an outsourcing facility under Section 503B, of the Federal Food, Drug, and Cosmetic Act. Buyers must be 21 or older.
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FDA & Legal Disclaimer. The statements on this website have not been evaluated by the U.S. Food and Drug Administration. Products offered by FNA Peptides are not intended to diagnose, treat, cure, or prevent any disease.
ALL PRODUCTS ARE SOLD FOR LABORATORY AND RESEARCH USE ONLY. THEY ARE NOT FOR HUMAN OR VETERINARY CONSUMPTION. FNA Peptides is a chemical supplier and is not a compounding pharmacy under Section 503A, nor an outsourcing facility under Section 503B, of the Federal Food, Drug, and Cosmetic Act. Customers must be 21 years of age or older, and are responsible for handling all materials in accordance with applicable local, state, and federal laws.
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